About the 2Go Study

This study is evaluating the safety and effectiveness of a study medication, called prucalopride, for children and teenagers with constipation. Prucalopride has already been approved in the United States for the treatment of constipation in adults.

The study is divided into three phases:

Phase Two

Study Treatment

If your child is eligible to participate in the 2Go Study, they will begin the Study Treatment Phase, which is broken into two parts, Part A and Part B.

For Part A, which lasts for 12 weeks, your child will be randomly assigned to 1 of 3 study treatment groups: high dose, low dose, and placebo
After Part A is completed, study participants who were in the placebo group for 12 weeks will be re-randomized into either the high- or low-dose group for Part B of the Study Treatment Phase, which lasts for 36 weeks
Part B of the Study Treatment Phase will measure the long-term safety of the study medication

Phase Three

Follow-up Phase

After Part A and Part B of the Study Treatment Phase are completed, there will be one follow-up visit to complete the study that takes place approximately 4 weeks after the last dose of the study medication is taken.

About the 2Go Study

This study is evaluating the safety and effectiveness of a study medication, called prucalopride, for children and teenagers with constipation. Prucalopride has already been approved in the United States for the treatment of constipation in adults.

The study is divided into three phases:

Screening

Study Treatment

Follow-up Phase

Please consider enrolling your child in the 2Go Study today.

If your child or teenager struggles with constipation, #2 may often be the #1 topic